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    普通Article chinese violet
    推荐Article Photograph of renal fibrosis
    普通Article Uremia
    推荐Article Jeopardize of uremia 
    推荐Article Why kidney disease change to uremia?
    普通Article Reversible phase of fibrosis formation
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    推荐Article Phase of scar formation
  • Shi Jia Zhuang Kidney Disease Hospital

  • Photograph of renal fibrosis

    nurse  

     

    Impel of kidney immanence's cell phenotype transform

    Excrete cause kidney toxicity cell gene and cell chemotaxis gene
            IL-1 TNF.ET.  PDGF  TGF-ß
        
    Stroma fibroblast to be activate
     
    Hyperplasia` and differentiation
       
    fibre-forming cell phenotype transform
     
    myofibroblast
     

    Excrete compose collagen 1,3
     
    Compose ECM quickly,degradation slowly  
     
    ECM abnormity accumulate and aggradation
     
    Fibrosis and cirrhosis of renal glomerulus,renal tubule, vessel of kidney,    stroma,

     

       

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