The Complications of Purpura Nephritis
2011-04-19 18:53
Purpura Nephritis is a kind of immunological disease characterized by necrotizing small vasculitis. The clinical symptoms are skin purpura, hemorrhagic gastroenteritis, arthritis, and renal impairment. The renal impairment is called Purpura Nephritis. People at any age can get this disease, especially in children under 10. The complications of Purpura Nephritis are as follows:
Rash
Rash is a kind of skin change. The symptoms vary from the simple skin color change to the upheaval or blister on the skin, and so on. At the beginning, there are different size of amaranthine purpuras on the surface, which do not fade even pressed. The purpuras can fuse into pieces, or exist like the shape of herpes, urticaria, or erythema multiforme, with angioedema sometimes.
When the disease is serious, ulcer and necrosis will happen. Purpuras are usually seen in the stretch side of arms and legs, buttocks, lower limbs, ankles, where joints are obvious. The purpuras appear symmetrically in batches, and recur easily.
Joint disease
Patients with Purpura Nephritis usually have the following symptoms: migrating, recurrent, arthralgia. The involved joints are in knees, ankles, and hands. The symptoms usually fade within several days and the joints will not be out of shape.
Some children suffer from joint swelling and pain, most of which involve big joints, such as knees, ankles, wrists, and elbows. It doesn’t influence the small joints. It can be single, multiple, and migrating. The joints swell, hurt, especially when the person is moving with low-grade fever partly, and even broiling heat for the serious case. There is no sequela after the symptoms disappear.
Urine tract disease.
For many children with Purpura Nephritis, there is a little protein and microscopic red blood cells. Sometimes, cast or gross hematuria can be seen. Purpura Nephritis usually have a good prognosis. During the process, rapidly progressive glomerulonephritis occur sometimes. But if the disease deteriorate into acute renal failure, the prognosis is bad. Some children with Purpura Nephritis also suffer from lots of proteinuria, hematuria, edema, hypotension, hypoproteinemia, and hypercholesterolemia, which is called Nephrotic Syndrome.
Gastrointestinal tract disease.
Patients with Purpura Nephritis usually have bellyache, mainly around the navel and in the inferior belly with paroxysmalcolikypain. The patients suffer from sickness, vomit, and bloody stool, with hematemesis sometimes. For Childhood Purpura Nephritis, indigitation, ileus, and enterobrosis may occur.
Hypertension
20%-40% high blood pressure diseases are caused by the Purpura Nephritis. The blood pressure increases in a light to a moderate way. Some patients with Purpura Nephritis can have hypertensive encephalopathy. The high blood pressure and abnormal urine often appear at the same time. But the majority of the patients with Purpura Nephritis revive rapidly.
So how to prevent Purpura Nephritis?Firstly, we should prevent cold, overstrain, excitement. Secondly, we had better take some food which is delicate, nutritious, and easy to absorb. Thirdly, we should remember not to eat too much, which can increase the burden of the stomach and intestine.
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