Susceptible Population of Diabetic Nephropathy
2010-12-09 18:00
Diabetic Nephropathy and Diabetic Microangiopathy will lead to ischemia and anoxia of renal tissues, increase of blood viscosity, decrease of erythrocyte deformability, increase of internal pressure of glomerular capillary basement membrane, increase of glomerulus arteriolar resistance, increase of afferent arteriole resistance and increase of ultrafiltrate pressure. Proteinuria, edema, renal failure and hypertension are the symptoms caused by damage of glomerular capillary basement membrane and arteriole.
The main manifestation of Microangiopathy is the concurrence of Diabetic Nephropathy glomerulosclerosis and diabetic retinopathy. The morbidity will increase with the prelonging of the course of disease. The kidney will increase in size, the GFR will increase and keep a high filtration status, thus the symptoms of interval proteinuria or MAU appearing. With the delaying of course of disease, there will be continuous proteinuria, edema, hypertension and decrease of GRF, which will result in renal insufficiency and Uremia.
As Diabetic Nephropathy is an life-threatening disease, experts call on everyone to be alarmed and actively prevent the occurring of Diabetic Nephropathy. Here are the Susceptible Population of Diabetic Nephropathy, who should be more careful.
1. People who have high blood sugar, and the difficulty in controlling blood sugar is the root cause.
2. People with hypertension. Hypertension is the accessary of Uremia, which can cause the a 6% decreasing of renal function each year.
3. Hereditary: it is a hereditary disease.
4. People who absorb more high protein: the high protein diet can increase the burden of kidneys, leading to the increase of albumin excretion through urine.
5. Patient with long course of disease: for Diabetes patients with more than 10 years of course of disease, the occurrence rate is 20% to 30%.
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